She specialized in pediatrics at Penteli Children's Hospital. As part of her specialization, she worked in the Neonatology Department of Elena Venizelou Maternity Hospital and later in the Neonatal Intensive Care Unit of the 2nd University Pediatric Clinic at Aglaya Kyriakou Children's Hospital. In 2011, she obtained the Neonatal Life Support certification, approved by the European Resuscitation Council.
In 2020, she completed the breastfeeding training program for healthcare professionals at the Institute of Child Health of the 1st University Pediatric Clinic of Agia Sophia Children's Hospital. Having completed over 150 training hours on breastfeeding, she acquired the proficiency to successfully support breastfeeding mothers.
In 2021, she completed a postgraduate program in infant and pediatric nutrition from the Boston University School of Medicine.
Until 2014, she was a research associate at the Alpha Institute of Biomedical Sciences in the field of pediatric infections, with publications in high-impact international scientific journals such as the Journal of Pediatrics and Intensive Care Medicine. She participated as a speaker at pan-European and global conferences, including the 5th Europediatrics meeting in Vienna in 2011 and the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco in 2009.
She was a founding member, responsible for managing pediatric cases and head of the quality assurance department of the innovative medical company Zante Medical Care, which provides healthcare services to international travelers and has strategic partnerships with global insurance providers and travel organizations to this day. In 2014, she received the significant certification 'Excellence in International Patient Care' from TEMOS.
She maintains a private practice in Glyfada, Attica, and is also an associate of the Pediatric Clinic at Mitera Hospital for the secondary care of her patients.
• Plessa E, Tansarli GS, Xanthopoulos D, Falagas ME. Morbidity and outcomes of foreign travelers in Zakynthos island, Greece: a retrospective study. PLoS One2014;9(4):e94416.
• Mantadakis Ε, Plessa Ε, Vouloumanou ΕΚ, MD, Michailidis L, Chatzimichael A, Falagas ME. Deep Venous Thrombosis in Children with Musculoskeletal Infections: The Clinical Evidence. Int J Infect Dis 2012; 16(4):e236-43.
• Vouloumanou EK, Plessa E, Karageorgopoulos DE, Mantadakis E, Falagas ME. Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis. Intensive care med 2011; 37(5):747-62.
• Plessa E, Diakakis P, Gardelis J, Thirios A, Koletsi P, Falagas ME. Clinical features, risk factors, and complications among pediatric patients with pandemic influenza A (H1N1). Clin Pediatr 2010; 49(8):777-81.
• Falagas ME, Vouloumanou EK, Plessa E, Peppas G, Rafailidis PI. Inaccuracies in dosing drugs with teaspoons-tablespoons. Int J Clin Pract 2010 Aug;64(9):1185-9.
• Bliziotis IA, Plessa E, Peppas G, Falagas ME. Daptomycin versus other antimicrobial agents for the treatment of skin and soft tissue infections: a meta-analysis. Ann Pharmacother 2010; 44(1): 97-106.
• Mantadakis Ε, Plessa E, Vouloumanou EK, Karageorgopoulos DE, Chatzimichael A, Falagas ME. Serum procalcitonin for prediction of renal parenchymal involvement in children with urinary tract infections: a meta-analysis of prospective clinical studies. J Pediatr 2009; 155(6): 875-881.
• 5th Europediatrics meeting. Vienna, June 2011. Mantadakis Ε, Plessa Ε, Vouloumanou ΕΚ, MD, Michailidis L, Chatzimichael A, Falagas ME. Deep Venous Thrombosis in Children with Musculoskeletal Infections: The Clinical Evidence.
• Excellence in pediatrics meeting. London, December 2010. Plessa E, Vouloumanou EK, Karageorgopoulos DE, Mantadakis E, Falagas ME. Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis.
• 49th interscience conference on antimicrobial agents and chemotherapy (ICAAC). San Francisco, September 2009. Mantadakis Ε, Plessa E, Vouloumanou EK, Karageorgopoulos DE, Chatzimichael A, Falagas ME. Serum procalcitonin for prediction of renal parenchymal involvement in children with urinary tract infections: a meta-analysis of prospective clinical studies.